BDBM251718 US10100018, Example 54::US9464060, 54

SMILES: OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1

InChI Key: InChIKey=BJSOAPDSLUIFGK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 251718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 5 (LPA5) (Homo sapiens (Human))	BDBM251718 (US10100018, Example 54 | US9464060, 54) Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251718 (US10100018, Example 54 | US9464060, 54) Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251718 (US10100018, Example 54 | US9464060, 54) Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251718 (US10100018, Example 54 | US9464060, 54) Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair