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SMILES: NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCN1C(=O)C1CNc2ccccc12

InChI Key: InChIKey=SWAURKKDQDEGLU-NNBQYGFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253007   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM253007
PNG
(US9469608, 35-7)
Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCN1C(=O)C1CNc2ccccc12 |r|
Show InChI InChI=1S/C21H23ClN4O2/c22-15-6-5-13(10-23)14(9-15)11-25-20(27)19-7-8-26(19)21(28)17-12-24-18-4-2-1-3-16(17)18/h1-6,9,17,19,24H,7-8,10-12,23H2,(H,25,27)/t17?,19-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 110n/an/an/an/an/an/a7.4n/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...

US Patent US9469608 (2016)


BindingDB Entry DOI: 10.7270/Q2F18XNQ
More data for this
Ligand-Target Pair