BDBM253009 US9469608, 37-11a

SMILES: CC1(C)C[C@@]1(O)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN

InChI Key: InChIKey=PTQZRJVGJCTSIV-HNAYVOBHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM253009 (US9469608, 37-11a) Show SMILES CC1(C)C[C@@]1(O)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CN |r| Show InChI InChI=1S/C19H26ClN3O3/c1-18(2)11-19(18,26)17(25)23-7-3-4-15(23)16(24)22-10-13-8-14(20)6-5-12(13)9-21/h5-6,8,15,26H,3-4,7,9-11,21H2,1-2H3,(H,22,24)/t15-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	720	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Relevant in vitro assays are referenced in Morrissette, et al., Bioorg. Med. Chem. Lett. 2004, 14, 4161-4164 and described in Lewis, et al. Thromb. R...				US Patent US9469608 (2016) BindingDB Entry DOI: 10.7270/Q2F18XNQ
					More data for this Ligand-Target Pair