null
SMILES: COc1ccc(COC(=O)C2=C(C)N=C3CC(CC(=O)C3C2c2cccs2)c2cccs2)cc1
InChI Key: InChIKey=LVJKPMXIISWWAP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP phosphoribosyltransferase (Mycobacterium tuberculosis) | BDBM25318 ((4-methoxyphenyl)methyl 2-methyl-5-oxo-4,7-bis(thi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 8.5 | 22 |
Yale University | Assay Description Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ... | J Med Chem 51: 5984-92 (2008) Article DOI: 10.1021/jm800328v BindingDB Entry DOI: 10.7270/Q2V986CX | |||||||||||
More data for this Ligand-Target Pair |