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BDBM25319 4,6-bis(benzylsulfanyl)pyrimidine-2,5-diamine::ChemBridge bis(benzylsulfanyl)pyrimidine, 15

SMILES: Nc1nc(SCc2ccccc2)c(N)c(SCc2ccccc2)n1

InChI Key: InChIKey=LHYPPLIXVIDZDS-UHFFFAOYSA-N

Data: 1 Other

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25319   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)		BDBM25319
PNG
(4,6-bis(benzylsulfanyl)pyrimidine-2,5-diamine | Ch...)
Show SMILES Nc1nc(SCc2ccccc2)c(N)c(SCc2ccccc2)n1
Show InChI InChI=1S/C18H18N4S2/c19-15-16(23-11-13-7-3-1-4-8-13)21-18(20)22-17(15)24-12-14-9-5-2-6-10-14/h1-10H,11-12,19H2,(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...

J Med Chem 51: 5984-92 (2008)


Article DOI: 10.1021/jm800328v
BindingDB Entry DOI: 10.7270/Q2V986CX
More data for this
Ligand-Target Pair