BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1c(F)cc(cc1F)C(O)=O

InChI Key: InChIKey=LJNLOXFAJIBKKX-ZOKDDAQRSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254040   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM254040
PNG
(US9493430, 593)
Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1c(F)cc(cc1F)C(O)=O |r,c:9|
Show InChI InChI=1S/C35H31F8NO5/c1-17-30(19-9-22(34(38,39)40)14-23(10-19)35(41,42)43)49-32(47)44(17)16-21-15-33(2,3)8-7-24(21)25-11-18(5-6-28(25)48-4)29-26(36)12-20(31(45)46)13-27(29)37/h5-6,9-14,17,30H,7-8,15-16H2,1-4H3,(H,45,46)/t17-,30-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a



Chong Kun Dang Pharmaceutical Corp.

US Patent


Assay Description
As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...

US Patent US9493430 (2016)


BindingDB Entry DOI: 10.7270/Q2W37V7V
More data for this
Ligand-Target Pair