BDBM254115 US9481677, 53

SMILES: Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-c1ccc2[nH]c(=O)oc2c1)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=PWSBSBCIWVSEHV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM254115 (US9481677, 53) Show SMILES Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-c1ccc2[nH]c(=O)oc2c1)S(=O)(=O)Nc1ncns1 Show InChI InChI=1S/C21H11ClF2N4O5S2/c22-11-2-4-16(12(6-11)10-1-3-15-18(5-10)33-21(29)27-15)32-17-7-14(24)19(8-13(17)23)35(30,31)28-20-25-9-26-34-20/h1-9H,(H,27,29)(H,25,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
XENON PHARMACEUTICALS INC. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (Nav's), and...				US Patent US9481677 (2016) BindingDB Entry DOI: 10.7270/Q20V8BQT
					More data for this Ligand-Target Pair