BDBM254117 US9481677, 55

SMILES: Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-c1ccc2CC(=O)Nc2c1)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=VLOASXUDBRPQJN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM254117 (US9481677, 55) Show SMILES Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-c1ccc2CC(=O)Nc2c1)S(=O)(=O)Nc1ncns1 Show InChI InChI=1S/C22H13ClF2N4O4S2/c23-13-3-4-18(14(7-13)11-1-2-12-6-21(30)28-17(12)5-11)33-19-8-16(25)20(9-15(19)24)35(31,32)29-22-26-10-27-34-22/h1-5,7-10H,6H2,(H,28,30)(H,26,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
XENON PHARMACEUTICALS INC. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (Nav's), and...				US Patent US9481677 (2016) BindingDB Entry DOI: 10.7270/Q20V8BQT
					More data for this Ligand-Target Pair