BDBM254475 US9468661, 53
SMILES: C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(C)=O)c2cc(OCc3ncccn3)c(C)cc12)[C@H]1CC1(Cl)Cl
InChI Key: InChIKey=AQZCADAHGOYLTO-HLFOTMJVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Complement factor D (Homo sapiens (Human)) | BDBM254475 (US9468661, 53) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG US Patent | Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun... | US Patent US9468661 (2016) BindingDB Entry DOI: 10.7270/Q23N22B5 | |||||||||||
More data for this Ligand-Target Pair |