BDBM25468 3,7-difluoro-2-nitro-9H-fluoren-9-one::NSC57476

SMILES: [O-][N+](=O)c1cc2C(=O)c3cc(F)ccc3-c2cc1F

InChI Key: InChIKey=DYURKAXDBWRFLK-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Phosphosulfate Reductase (APSR) (Mycobacterium tuberculosis)	BDBM25468 (3,7-difluoro-2-nitro-9H-fluoren-9-one | NSC57476) Show SMILES [O-][N+](=O)c1cc2C(=O)c3cc(F)ccc3-c2cc1F Show InChI InChI=1S/C13H5F2NO3/c14-6-1-2-7-8-4-11(15)12(16(18)19)5-10(8)13(17)9(7)3-6/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.46E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
					More data for this Ligand-Target Pair