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SMILES: CN(C)CCOc1cc(ccc1N)-c1cn[nH]c1

InChI Key: InChIKey=QLQDFBOLZONHCZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25475   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2 [1-543,T431N]


(Homo sapiens (Human))		BDBM25475
PNG
(2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)ani...)
Show SMILES CN(C)CCOc1cc(ccc1N)-c1cn[nH]c1
Show InChI InChI=1S/C13H18N4O/c1-17(2)5-6-18-13-7-10(3-4-12(13)14)11-8-15-16-9-11/h3-4,7-9H,5-6,14H2,1-2H3,(H,15,16)
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 920n/an/an/an/a7.022



The Scripps Research Institute



Assay Description
Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...

J Med Chem 51: 6642-5 (2008)


Article DOI: 10.1021/jm800986w
BindingDB Entry DOI: 10.7270/Q2JS9NRN
More data for this
Ligand-Target Pair