BDBM254961 US9505765, 184

SMILES: CC(C)COc1ncnc2[nH]cc(\C=C\C(=O)N(C)C)c12

InChI Key: InChIKey=OMSUAZHPXSYOQO-AATRIKPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Homo sapiens (Human))	BDBM254961 (US9505765, 184) Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(=O)N(C)C)c12 Show InChI InChI=1S/C15H20N4O2/c1-10(2)8-21-15-13-11(5-6-12(20)19(3)4)7-16-14(13)17-9-18-15/h5-7,9-10H,8H2,1-4H3,(H,16,17,18)/b6-5+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
CONFLUENCE LIFE SCIENCES INC. US Patent					Assay Description TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...				US Patent US9505765 (2016) BindingDB Entry DOI: 10.7270/Q2T43S1J
					More data for this Ligand-Target Pair