null
SMILES: CC(C)Oc1ncnc2[nH]cc(\C=C\C(N)=O)c12
InChI Key: InChIKey=YQZZHUQLRWPXNZ-ONEGZZNKSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Homo sapiens (Human)) | BDBM254964 (US9505765, 188) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
CONFLUENCE LIFE SCIENCES INC. US Patent | Assay Description TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi... | US Patent US9505765 (2016) BindingDB Entry DOI: 10.7270/Q2T43S1J | |||||||||||
More data for this Ligand-Target Pair |