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SMILES: NC(=O)\C=C\c1c[nH]c2ncnc(OCC(F)(F)F)c12

InChI Key: InChIKey=BKXGJUGZEFIAJO-OWOJBTEDSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254967   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1


(Homo sapiens (Human))		BDBM254967
PNG
(US9505765, 191)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OCC(F)(F)F)c12
Show InChI InChI=1S/C11H9F3N4O2/c12-11(13,14)4-20-10-8-6(1-2-7(15)19)3-16-9(8)17-5-18-10/h1-3,5H,4H2,(H2,15,19)(H,16,17,18)/b2-1+
PDB

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US Patent
n/an/a 33n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...

US Patent US9505765 (2016)


BindingDB Entry DOI: 10.7270/Q2T43S1J
More data for this
Ligand-Target Pair