BDBM25505 1-(3-methoxyphenyl)-3-methyl-N-[(1S)-1-phenylethyl]-1H-pyrazolo[4,3-c]pyridin-6-amine::2-amino-pyrazolopyridine, 10

SMILES: COc1cccc(c1)-n1nc(C)c2cnc(N[C@@H](C)c3ccccc3)cc12

InChI Key: InChIKey=AVCWXYCDBRFSPG-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM25505 (1-(3-methoxyphenyl)-3-methyl-N-[(1S)-1-phenylethyl...) Show SMILES COc1cccc(c1)-n1nc(C)c2cnc(N[C@@H](C)c3ccccc3)cc12 |r| Show InChI InChI=1S/C22H22N4O/c1-15(17-8-5-4-6-9-17)24-22-13-21-20(14-23-22)16(2)25-26(21)18-10-7-11-19(12-18)27-3/h4-15H,1-3H3,(H,23,24)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.93E+3	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5648-52 (2008) Article DOI: 10.1016/j.bmcl.2008.08.095 BindingDB Entry DOI: 10.7270/Q29C6VRP
					More data for this Ligand-Target Pair