BindingDB logo
myBDB logout

null

SMILES: Cn1cc(c(n1)-c1cnco1)-c1ccc2C(CCc2c1)N=O

InChI Key: InChIKey=ZLUOUODRGRXXJG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25644   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM25644
PNG
((1Z)-5-[1-methyl-3-(1,3-oxazol-5-yl)-1H-pyrazol-4-...)
Show SMILES Cn1cc(c(n1)-c1cnco1)-c1ccc2C(CCc2c1)N=O
Show InChI InChI=1S/C16H14N4O2/c1-20-8-13(16(18-20)15-7-17-9-22-15)11-2-4-12-10(6-11)3-5-14(12)19-21/h2,4,6-9,14H,3,5H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10n/an/an/an/a7.222



Array BioPharma



Assay Description
Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...

Bioorg Med Chem Lett 18: 4692-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.002
BindingDB Entry DOI: 10.7270/Q2NK3CBJ
More data for this
Ligand-Target Pair