BindingDB logo
myBDB logout

null

SMILES: Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)C(=N)NO

InChI Key: InChIKey=QYBPQELFZBKETA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25648   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM25648
PNG
(N'-hydroxy-4-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol...)
Show SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)C(=N)NO
Show InChI InChI=1S/C16H15N5O/c1-21-10-14(15(19-21)12-6-8-18-9-7-12)11-2-4-13(5-3-11)16(17)20-22/h2-10,22H,1H3,(H2,17,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18.4n/an/an/an/an/an/a



Array BioPharma



Assay Description
Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...

Bioorg Med Chem Lett 18: 4692-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.002
BindingDB Entry DOI: 10.7270/Q2NK3CBJ
More data for this
Ligand-Target Pair