BDBM25651 4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyrazol-3-yl}pyridine::pyrazole based inhibitor, 33

SMILES: Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)-c1cc[nH]n1

InChI Key: InChIKey=ZZGACVWRPAHSSW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM25651 (4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyraz...) Show SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)-c1cc[nH]n1 Show InChI InChI=1S/C18H15N5/c1-23-12-16(18(22-23)15-6-9-19-10-7-15)13-2-4-14(5-3-13)17-8-11-20-21-17/h2-12H,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of B-Raf				Bioorg Med Chem Lett 21: 3488-92 (2011) Article DOI: 10.1016/j.bmcl.2010.12.038 BindingDB Entry DOI: 10.7270/Q20R9PQ9
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM25651 (4-{1-methyl-4-[4-(1H-pyrazol-3-yl)phenyl]-1H-pyraz...) Show SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc(cc1)-c1cc[nH]n1 Show InChI InChI=1S/C18H15N5/c1-23-12-16(18(22-23)15-6-9-19-10-7-15)13-2-4-14(5-3-13)17-8-11-20-21-17/h2-12H,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68.4	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma					Assay Description Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...				Bioorg Med Chem Lett 18: 4692-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.002 BindingDB Entry DOI: 10.7270/Q2NK3CBJ
					More data for this Ligand-Target Pair