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SMILES: Cn1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1

InChI Key: InChIKey=MAOYHJWWEYWDEQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25653   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM25653
PNG
(4-(4-{2H,4H-indeno[1,2-c]pyrazol-6-yl}-1-methyl-1H...)
Show SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1
Show InChI InChI=1S/C19H15N5/c1-24-11-17(19(23-24)12-4-6-20-7-5-12)13-2-3-16-14(8-13)9-15-10-21-22-18(15)16/h2-8,10-11H,9H2,1H3,(H,21,22)
PDB
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Similars
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a



Array BioPharma



Assay Description
Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...

Bioorg Med Chem Lett 18: 4692-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.002
BindingDB Entry DOI: 10.7270/Q2NK3CBJ
More data for this
Ligand-Target Pair