BDBM25670 5-bromo-N-(4-methoxyphenyl)-1,3-thiazol-2-amine::aminothiazole analogue, 14

SMILES: COc1ccc(Nc2ncc(Br)s2)cc1

InChI Key: InChIKey=SVYOYUOJJWKYDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25670 (5-bromo-N-(4-methoxyphenyl)-1,3-thiazol-2-amine | ...) Show SMILES COc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H9BrN2OS/c1-14-8-4-2-7(3-5-8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair