BDBM25688 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(morpholin-4-yl)ethyl]benzamide::aminothiazole analogue, 32

SMILES: Brc1cnc(Nc2ccc(cc2)C(=O)NCCN2CCOCC2)s1

InChI Key: InChIKey=TUORUMAUQXCXFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25688 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(morpholi...) Show SMILES Brc1cnc(Nc2ccc(cc2)C(=O)NCCN2CCOCC2)s1 Show InChI InChI=1S/C16H19BrN4O2S/c17-14-11-19-16(24-14)20-13-3-1-12(2-4-13)15(22)18-5-6-21-7-9-23-10-8-21/h1-4,11H,5-10H2,(H,18,22)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair