BDBM25694 5-bromo-N-[3-(methylsulfanyl)phenyl]-1,3-thiazol-2-amine::aminothiazole analogue, 38

SMILES: CSc1cccc(Nc2ncc(Br)s2)c1

InChI Key: InChIKey=LZXFIXLCRDSHDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25694 (5-bromo-N-[3-(methylsulfanyl)phenyl]-1,3-thiazol-2...) Show SMILES CSc1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C10H9BrN2S2/c1-14-8-4-2-3-7(5-8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair