BDBM25698 3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyethyl)benzamide::aminothiazole analogue, 42

SMILES: COCCNC(=O)c1cccc(Nc2ncc(Br)s2)c1

InChI Key: InChIKey=JLTGNOUTGNZYHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25698 (3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...) Show SMILES COCCNC(=O)c1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C13H14BrN3O2S/c1-19-6-5-15-12(18)9-3-2-4-10(7-9)17-13-16-8-11(14)20-13/h2-4,7-8H,5-6H2,1H3,(H,15,18)(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair