BDBM25706 5-bromo-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine::aminothiazole analogue, 50

SMILES: Clc1ccc(Nc2ncc(Br)s2)cc1Cl

InChI Key: InChIKey=RPALQLSAGKQQRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25706 (5-bromo-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine...) Show SMILES Clc1ccc(Nc2ncc(Br)s2)cc1Cl Show InChI InChI=1S/C9H5BrCl2N2S/c10-8-4-13-9(15-8)14-5-1-2-6(11)7(12)3-5/h1-4H,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair