BDBM25712 N-(5-bromo-1,3-thiazol-2-yl)benzamide::aminothiazole analogue, 56

SMILES: Brc1cnc(NC(=O)c2ccccc2)s1

InChI Key: InChIKey=RNOLMRKXWGXDQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25712 (N-(5-bromo-1,3-thiazol-2-yl)benzamide | aminothiaz...) Show SMILES Brc1cnc(NC(=O)c2ccccc2)s1 Show InChI InChI=1S/C10H7BrN2OS/c11-8-6-12-10(15-8)13-9(14)7-4-2-1-3-5-7/h1-6H,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair