BDBM25807 4,4 -Dihydroxybenzophenone::4-[(4-hydroxyphenyl)carbonyl]phenol::Bis(p-hydroxy)benzophenone::Compound 0627-0373 (DHBP)::US9688816, N

SMILES: Oc1ccc(cc1)C(=O)c1ccc(O)cc1

InChI Key: InChIKey=RXNYJUSEXLAVNQ-UHFFFAOYSA-N

Data: 3 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol 14-alpha demethylase (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM25807 (4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C13H10O3/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,14-15H	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	7.5	37
University of California at San Francisco					Assay Description The assay was developed based on the optical spectral property of P450 enzyme to elicit both type I and type II spectral changes (350 nm through 450 ...				Antimicrob Agents Chemother 51: 3915-23 (2007) Article DOI: 10.1128/AAC.00311-07 BindingDB Entry DOI: 10.7270/Q20V8B3R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM25807 (4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C13H10O3/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,14-15H	PDB GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...				US Patent US9688816 (2017) BindingDB Entry DOI: 10.7270/Q2WD3XR0
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM25807 (4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C13H10O3/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,14-15H	PDB GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...				US Patent US9688816 (2017) BindingDB Entry DOI: 10.7270/Q2WD3XR0
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM25807 (4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...) Show SMILES Oc1ccc(cc1)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C13H10O3/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,14-15H	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Basel Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)				J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ
					More data for this Ligand-Target Pair