BDBM25849 4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol::CHEMBL204010::hydroxyphenyl substituted thiophene, 21

SMILES: Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1

InChI Key: InChIKey=KZMOBYGIRBRCFV-UHFFFAOYSA-N

Data: 1 KI  2 EC50  1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM25849 (4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | CHEMB...) Show SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1 Show InChI InChI=1S/C16H12O2S/c17-13-5-1-11(2-6-13)15-9-10-16(19-15)12-3-7-14(18)8-4-12/h1-10,17-18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates				Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM25849 (4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | CHEMB...) Show SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1 Show InChI InChI=1S/C16H12O2S/c17-13-5-1-11(2-6-13)15-9-10-16(19-15)12-3-7-14(18)8-4-12/h1-10,17-18H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University) Curated by ChEMBL					Assay Description Agonist activity at estrogen receptor alpha (unknown origin) expressed in human HepG2 cells coexpressing estrogen response element after 24 hrs by lu...				J Med Chem 56: 3346-66 (2013) Article DOI: 10.1021/jm400157e BindingDB Entry DOI: 10.7270/Q2MK6F7V
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM25849 (4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | CHEMB...) Show SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1 Show InChI InChI=1S/C16H12O2S/c17-13-5-1-11(2-6-13)15-9-10-16(19-15)12-3-7-14(18)8-4-12/h1-10,17-18H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University) Curated by ChEMBL					Assay Description Agonist activity at estrogen receptor beta (unknown origin) expressed in human HepG2 cells coexpressing estrogen response element after 24 hrs by luc...				J Med Chem 56: 3346-66 (2013) Article DOI: 10.1021/jm400157e BindingDB Entry DOI: 10.7270/Q2MK6F7V
					More data for this Ligand-Target Pair
17-beta-Hydroxysteroid Dehydrogenase 1 (17-beta-HSD1) (Homo sapiens (Human))	BDBM25849 (4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | CHEMB...) Show SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1 Show InChI InChI=1S/C16H12O2S/c17-13-5-1-11(2-6-13)15-9-10-16(19-15)12-3-7-14(18)8-4-12/h1-10,17-18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.0	37
Saarland University					Assay Description Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...				J Med Chem 51: 6725-39 (2008) Article DOI: 10.1021/jm8006917 BindingDB Entry DOI: 10.7270/Q2RB72XG
					More data for this Ligand-Target Pair