BDBM2594 (Arylindolyl)maleimide deriv. 16::3-(1-methyl-1H-indol-3-yl)-4-(1-phenyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cn(-c3ccccc3)c3ccccc23)c2ccccc12

InChI Key: InChIKey=LZSMYZZPCOFKOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2594 ((Arylindolyl)maleimide deriv. 16 | 3-(1-methyl-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(-c3ccccc3)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H19N3O2/c1-29-15-20(18-11-5-7-13-22(18)29)24-25(27(32)28-26(24)31)21-16-30(17-9-3-2-4-10-17)23-14-8-6-12-19(21)23/h2-16H,1H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair