Found 4 hits for monomerid = 259461 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM259461
(US9512114, 26)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C25H25N9O2/c1-13(30-23-21(22(26)27-12-28-23)24-31-14(2)32-36-24)19-9-15-5-4-6-18(16-10-29-33(3)11-16)20(15)25(35)34(19)17-7-8-17/h4-6,9-13,17H,7-8H2,1-3H3,(H3,26,27,28,30)/t13-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM259461
(US9512114, 26)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C25H25N9O2/c1-13(30-23-21(22(26)27-12-28-23)24-31-14(2)32-36-24)19-9-15-5-4-6-18(16-10-29-33(3)11-16)20(15)25(35)34(19)17-7-8-17/h4-6,9-13,17H,7-8H2,1-3H3,(H3,26,27,28,30)/t13-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 176 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p1103/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as requ... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM259461
(US9512114, 26)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C25H25N9O2/c1-13(30-23-21(22(26)27-12-28-23)24-31-14(2)32-36-24)19-9-15-5-4-6-18(16-10-29-33(3)11-16)20(15)25(35)34(19)17-7-8-17/h4-6,9-13,17H,7-8H2,1-3H3,(H3,26,27,28,30)/t13-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p120γ) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as required)... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM259461
(US9512114, 26)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C25H25N9O2/c1-13(30-23-21(22(26)27-12-28-23)24-31-14(2)32-36-24)19-9-15-5-4-6-18(16-10-29-33(3)11-16)20(15)25(35)34(19)17-7-8-17/h4-6,9-13,17H,7-8H2,1-3H3,(H3,26,27,28,30)/t13-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
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