BDBM259470 US9512126, 8
SMILES: COc1cccc(c1)C(=C)c1cc(NCCC(F)(F)F)c2ncc(-c3ccc(C(=O)NC4CC4)c(C)c3)n2n1
InChI Key: InChIKey=UOLCKKXWOYEFJA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GST-Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM259470 (US9512126, 8) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.7 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description The human kinase Mps-1 phosphorylates a biotinylated substrate peptide. Detection of the phosphorylated product is achieved by time-resolved fluoresc... | US Patent US9512126 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z5S | |||||||||||
More data for this Ligand-Target Pair |