new BindingDB logo
myBDB logout

BDBM2595 (Arylindolyl)maleimide deriv. 17::3-(1-methyl-1H-indol-2-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cc3ccccc3n2C)c2ccccc12

InChI Key: InChIKey=MYVWPFIWWMGBTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2595   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C


(Rattus norvegicus (rat))
BDBM2595
PNG
((Arylindolyl)maleimide deriv. 17 | 3-(1-methyl-1H-...)
Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cc3ccccc3n2C)c2ccccc12 |t:4|
Show InChI InChI=1S/C22H17N3O2/c1-24-12-15(14-8-4-6-10-17(14)24)19-20(22(27)23-21(19)26)18-11-13-7-3-5-9-16(13)25(18)2/h3-12H,1-2H3,(H,23,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a7.530



Roche Products Limited



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


J Med Chem 35: 177-84 (1992)


Article DOI: 10.1016/j.bmc.2005.03.050
BindingDB Entry DOI: 10.7270/Q2K64G8V
More data for this
Ligand-Target Pair