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SMILES: CN(CCO)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N

InChI Key: InChIKey=YKHGZHUCBLLAOL-SFQUDFHCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259867   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3 [399-740]


(Homo sapiens (Human))		BDBM259867
PNG
(US9505766, 72)
Show SMILES CN(CCO)C(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N
Show InChI InChI=1S/C23H26N6O3/c1-15-4-6-16(7-5-15)19-18(12-17(13-24)23(32)28(2)9-11-31)29(8-3-10-30)22-20(19)21(25)26-14-27-22/h4-7,12,14,30-31H,3,8-11H2,1-2H3,(H2,25,26,27)/b17-12+
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/a8.022



THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

US Patent


Assay Description
RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...

US Patent US9505766 (2016)


BindingDB Entry DOI: 10.7270/Q2639NPR
More data for this
Ligand-Target Pair