null
SMILES: FC(F)CCOc1ccc([C@H]2COC(=O)N2c2ccc3[nH]cnc3c2)c(F)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human)) | BDBM259899 (US9512115, 2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.54 | -11.3 | n/a | n/a | n/a | n/a | n/a | 8.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human)) | BDBM259899 (US9512115, 2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.5 | -11.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair |