BDBM259916 US9512115, 20
SMILES: Fc1cc(cc(F)c1[C@H]1COC(=O)N1c1ccc2[nH]cnc2c1)N1CCC(F)(F)C1
InChI Key:
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl Cyclase (Homo sapiens (Human)) | BDBM259916 (US9512115, 20) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.53 | -11.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutaminyl Cyclase (Homo sapiens (Human)) | BDBM259916 (US9512115, 20) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.29 | -11.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair |