null
SMILES: Fc1cc(ccc1N1CCC(F)(F)C1)[C@H]1COC(=O)N1c1ccc2[nH]cnc2c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human)) | BDBM259917 (US9512115, 21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 10.4 | -11.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human)) | BDBM259917 (US9512115, 21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 16.7 | -10.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 30 |
PROBIODRUG AG US Patent | Assay Description All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometr... | US Patent US9512115 (2016) BindingDB Entry DOI: 10.7270/Q2XK8DG4 | |||||||||||
More data for this Ligand-Target Pair |