BDBM260139 US9522886, 87

SMILES: NC(=O)CC1(CCOC1)NC(=O)c1ccc(C2CC2)c(Oc2ccc(F)cc2)n1

InChI Key: InChIKey=WGPSUDKSIIRCJL-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260139 (US9522886, 87) Show SMILES NC(=O)CC1(CCOC1)NC(=O)c1ccc(C2CC2)c(Oc2ccc(F)cc2)n1 Show InChI InChI=1S/C21H22FN3O4/c22-14-3-5-15(6-4-14)29-20-16(13-1-2-13)7-8-17(24-20)19(27)25-21(11-18(23)26)9-10-28-12-21/h3-8,13H,1-2,9-12H2,(H2,23,26)(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	34.8	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260139 (US9522886, 87) Show SMILES NC(=O)CC1(CCOC1)NC(=O)c1ccc(C2CC2)c(Oc2ccc(F)cc2)n1 Show InChI InChI=1S/C21H22FN3O4/c22-14-3-5-15(6-4-14)29-20-16(13-1-2-13)7-8-17(24-20)19(27)25-21(11-18(23)26)9-10-28-12-21/h3-8,13H,1-2,9-12H2,(H2,23,26)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair