BDBM2603 (Arylindolyl)maleimide deriv. 25::3-(1-methyl-1H-indol-3-yl)-4-(thiophen-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2ccsc2)c2ccccc12

InChI Key: InChIKey=QSWVIVJBWVSRRV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2603 ((Arylindolyl)maleimide deriv. 25 | 3-(1-methyl-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2ccsc2)c2ccccc12 |t:4| Show InChI InChI=1S/C17H12N2O2S/c1-19-8-12(11-4-2-3-5-13(11)19)15-14(10-6-7-22-9-10)16(20)18-17(15)21/h2-9H,1H3,(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair