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BDBM260857 US9540323, 44::US9540323, example 44

SMILES: CCC1(CC)CN(c2c1c(ccc2O)C#N)c1ccccc1NC(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=ARZBDQHDPIIUCN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260857   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purinergic receptor P2Y1


(Homo sapiens (Human))		BDBM260857
PNG
(US9540323, 44 | US9540323, example 44)
Show SMILES CCC1(CC)CN(c2c1c(ccc2O)C#N)c1ccccc1NC(=O)Nc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C30H34N4O2/c1-6-30(7-2)19-34(27-25(35)17-12-20(18-31)26(27)30)24-11-9-8-10-23(24)33-28(36)32-22-15-13-21(14-16-22)29(3,4)5/h8-17,35H,6-7,19H2,1-5H3,(H2,32,33,36)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6.90 -11.1n/an/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...

US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair