BDBM260861 US9540323, 48::US9540323, example 48

SMILES: CCC1(CC)CN(c2c1c(Cl)ccc2O)c1ccccc1NC(=O)Nc1nc(ns1)C(C)C

InChI Key: InChIKey=ZVGJFPDPSIEASE-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM260861 (US9540323, 48 | US9540323, example 48) Show SMILES CCC1(CC)CN(c2c1c(Cl)ccc2O)c1ccccc1NC(=O)Nc1nc(ns1)C(C)C Show InChI InChI=1S/C24H28ClN5O2S/c1-5-24(6-2)13-30(20-18(31)12-11-15(25)19(20)24)17-10-8-7-9-16(17)26-22(32)28-23-27-21(14(3)4)29-33-23/h7-12,14,31H,5-6,13H2,1-4H3,(H2,26,27,28,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7	-11.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...				US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P
					More data for this Ligand-Target Pair