BDBM260871 US9540323, 59::US9540323, example 59

SMILES: CC1(C)CN(c2c1c(ccc2O)C(F)(F)F)c1cc(F)ccc1NC(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=DPAMWTMZNZQKBI-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM260871 (US9540323, 59 | US9540323, example 59) Show SMILES CC1(C)CN(c2c1c(ccc2O)C(F)(F)F)c1cc(F)ccc1NC(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C24H19F6N3O2/c1-23(2)11-33(21-19(34)8-5-14(20(21)23)24(28,29)30)18-10-13(26)4-7-17(18)32-22(35)31-16-6-3-12(25)9-15(16)27/h3-10,34H,11H2,1-2H3,(H2,31,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.70	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...				US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P
					More data for this Ligand-Target Pair