BDBM2609 3-(5-Hydroxy-1-methyl-3-indolyl)-4-(1-methyl-3-indolyl)pyrrole-2,5-dione::3-(5-hydroxy-1-methyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 31

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccc(O)cc23)c2ccccc12

InChI Key: InChIKey=CQVGLBTZZGJXTR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2609 (3-(5-Hydroxy-1-methyl-3-indolyl)-4-(1-methyl-3-ind...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccc(O)cc23)c2ccccc12 |t:4| Show InChI InChI=1S/C22H17N3O3/c1-24-10-15(13-5-3-4-6-17(13)24)19-20(22(28)23-21(19)27)16-11-25(2)18-8-7-12(26)9-14(16)18/h3-11,26H,1-2H3,(H,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair