Found 15 hits for monomerid = 26109 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Solute carrier family 22 member 20
(Mus musculus) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | KEGG
UniProtKB/SwissProt
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| Article PubMed
| 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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| Article PubMed
| 1.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University
Curated by ChEMBL
| Assay Description Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assay |
Bioorg Med Chem 17: 5219-28 (2009)
Article DOI: 10.1016/j.bmc.2009.05.042 BindingDB Entry DOI: 10.7270/Q22F7R82 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
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| 3.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC3 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC8 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC4 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC5 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC7 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC9 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 6
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC6 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Free fatty acid receptor 3
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a |
Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Curated by ChEMBL
| Assay Description Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method |
J Med Chem 61: 47-61 (2018)
Article DOI: 10.1021/acs.jmedchem.7b00244 BindingDB Entry DOI: 10.7270/Q2JD507R |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC2 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC1 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone Lysine Demethylase
(Homo sapiens (Human)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | PDB MMDB
KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Oxford
| Assay Description A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy... |
J Med Chem 51: 7053-6 (2008)
Article DOI: 10.1021/jm800936s BindingDB Entry DOI: 10.7270/Q2959FV4 |
More data for this Ligand-Target Pair | |
Methyl-accepting chemotaxis protein (McpS)
(Pseudomonas putida (Arthrobacter siderocapsulatus)) | BDBM26109
(Butyrate | butanoic acid | butanoic acid, 4)Show InChI InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6) | KEGG
UniProtKB/SwissProt
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | 20 |
CSIC
| Assay Description Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA). |
J Biol Chem 285: 23126-36 (2010)
Article DOI: 10.1074/jbc.M110.110403 BindingDB Entry DOI: 10.7270/Q2K64GNS |
More data for this Ligand-Target Pair | |