BDBM2611 3-[5-(benzyloxy)-1-methyl-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 33

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccc(OCc4ccccc4)cc23)c2ccccc12

InChI Key: InChIKey=VVOIKNNKVBSZJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2611 (3-[5-(benzyloxy)-1-methyl-1H-indol-3-yl]-4-(1-meth...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccc(OCc4ccccc4)cc23)c2ccccc12 |t:4| Show InChI InChI=1S/C29H23N3O3/c1-31-15-22(20-10-6-7-11-24(20)31)26-27(29(34)30-28(26)33)23-16-32(2)25-13-12-19(14-21(23)25)35-17-18-8-4-3-5-9-18/h3-16H,17H2,1-2H3,(H,30,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair