null

SMILES: CCOc1c(cc(Cl)c(C)c1-c1cnn(CC(=O)N(C)C)c1)C(C)Nc1ncnc(N)c1C(C)=N

InChI Key: InChIKey=TXPNJNMCCIOYRG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform (Homo sapiens (Human))	BDBM261182 (2-(4-(3-(1-(4-amino-3-methyl-1H- pyrazolo[3,4-d]py...) Show SMILES CCOc1c(cc(Cl)c(C)c1-c1cnn(CC(=O)N(C)C)c1)C(C)Nc1ncnc(N)c1C(C)=N Show InChI InChI=1S/C24H31ClN8O2/c1-7-35-22-17(15(4)31-24-21(14(3)26)23(27)28-12-29-24)8-18(25)13(2)20(22)16-9-30-33(10-16)11-19(34)32(5)6/h8-10,12,15,26H,7,11H2,1-6H3,(H3,27,28,29,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	6.7	25
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...				US Patent US9707233 (2017) BindingDB Entry DOI: 10.7270/Q2S46V0R
					More data for this Ligand-Target Pair