BDBM26134 (4-nonylphenyl)boranediol::Phenylboronic Acid, 13

SMILES: CCCCCCCCCc1ccc(cc1)B(O)O

InChI Key: InChIKey=VONVJOGSLHAKOX-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 26134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	7.4	37
University of Oxford					Assay Description [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...				J Med Chem 51: 7057-60 (2008) Article DOI: 10.1021/jm801051t BindingDB Entry DOI: 10.7270/Q25D8Q58
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford					Assay Description The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...				J Med Chem 51: 7057-60 (2008) Article DOI: 10.1021/jm801051t BindingDB Entry DOI: 10.7270/Q25D8Q58
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting method				Bioorg Med Chem Lett 26: 1401-5 (2016) BindingDB Entry DOI: 10.7270/Q24F1SM9
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f...				Bioorg Med Chem Lett 26: 1401-5 (2016) BindingDB Entry DOI: 10.7270/Q24F1SM9
					More data for this Ligand-Target Pair