BDBM26172 2,4-dianilino pyrimidine, 29::3-({4-[(1-methyl-1H-1,3-benzodiazol-5-yl)amino]pyrimidin-2-yl}amino)benzamide

SMILES: Cn1cnc2cc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)ccc12

InChI Key: InChIKey=DKRWNOCNKJWJED-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lck (Mus musculus)	BDBM26172 (2,4-dianilino pyrimidine, 29 | 3-({4-[(1-methyl-1H...) Show SMILES Cn1cnc2cc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)ccc12 Show InChI InChI=1S/C19H17N7O/c1-26-11-22-15-10-14(5-6-16(15)26)23-17-7-8-21-19(25-17)24-13-4-2-3-12(9-13)18(20)27/h2-11H,1H3,(H2,20,27)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair