null
SMILES: O[C@H]1CCCC[C@@H]1NC(=O)c1cc(CN2CCC(CC2)(C#N)c2ccccn2)c2ccccc2c1F
InChI Key: InChIKey=VMJJGOKGXBMAEQ-DQEYMECFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (RAT) | BDBM261740 (4-((4-Cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 345 | n/a | n/a | n/a | n/a |
HOFFMANN-LA-ROCHE INC. US Patent | Assay Description The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin... | US Patent US9708302 (2017) BindingDB Entry DOI: 10.7270/Q2BV7JMP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM261740 (4-((4-Cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 258 | n/a | n/a | n/a | n/a |
HOFFMANN-LA-ROCHE INC. US Patent | Assay Description The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin... | US Patent US9708302 (2017) BindingDB Entry DOI: 10.7270/Q2BV7JMP | |||||||||||
More data for this Ligand-Target Pair |