BDBM261746 US10233178, Example 13::US9708309, 13

SMILES: Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1

InChI Key: InChIKey=OESPUGOBLAXSPX-SJORKVTESA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 261746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...				US Patent US9708309 (2017) BindingDB Entry DOI: 10.7270/Q2736SXQ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...				US Patent US9708309 (2017) BindingDB Entry DOI: 10.7270/Q2736SXQ
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono					Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...				J Med Chem 51: 2227-2243 (2008) BindingDB Entry DOI: 10.7270/Q2V69MWZ
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono					Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...				J Med Chem 51: 2227-2243 (2008) BindingDB Entry DOI: 10.7270/Q2V69MWZ
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono					Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...				J Med Chem 51: 2227-2243 (2008) BindingDB Entry DOI: 10.7270/Q2V69MWZ
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM261746 (US10233178, Example 13 | US9708309, 13) Show SMILES Nc1nnc(CN[C@H]2C[C@@H]2c2ccc(OCc3cc(F)cc(F)c3)cc2)o1 |r| Show InChI InChI=1S/C19H18F2N4O2/c20-13-5-11(6-14(21)7-13)10-26-15-3-1-12(2-4-15)16-8-17(16)23-9-18-24-25-19(22)27-18/h1-7,16-17,23H,8-10H2,(H2,22,25)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ORYZON GENOMICS, S.A. US Patent					Assay Description Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...				US Patent US9708309 (2017) BindingDB Entry DOI: 10.7270/Q2736SXQ
					More data for this Ligand-Target Pair