BDBM2618 Bisindolylmaleimide deriv. 40::N-{1-methyl-3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-5-yl}acetamide

SMILES: CC(=O)Nc1ccc2n(C)cc(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c2c1

InChI Key: InChIKey=IODCGJGLMDWAMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2618 (Bisindolylmaleimide deriv. 40 | N-{1-methyl-3-[4-(...) Show SMILES CC(=O)Nc1ccc2n(C)cc(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c2c1 |t:12| Show InChI InChI=1S/C24H20N4O3/c1-13(29)25-14-8-9-20-16(10-14)18(12-28(20)3)22-21(23(30)26-24(22)31)17-11-27(2)19-7-5-4-6-15(17)19/h4-12H,1-3H3,(H,25,29)(H,26,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair