Found 56 hits for monomerid = 26188 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00256 BindingDB Entry DOI: 10.7270/Q23X8BQF |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 3
(Bos taurus (Cattle)) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.79E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ondokuz Mayis University
| Assay Description The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s... |
J Enzyme Inhib Med Chem 27: 845-8 (2012)
Article DOI: 10.3109/14756366.2011.621122 BindingDB Entry DOI: 10.7270/Q27P8X9X |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po... |
Bioorg Med Chem 25: 1481-1486 (2017)
Article DOI: 10.1016/j.bmc.2017.01.012 BindingDB Entry DOI: 10.7270/Q2028TQP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
E3 ubiquitin-protein ligase Mdm2
(Homo sapiens (Human)) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by ChEMBL
| Assay Description Inhibition of biotin-labelled p53 binding to MDM2 (25 to 109 residues) (unknown origin) by surface plasmon resonance method |
Bioorg Med Chem Lett 27: 2571-2574 (2017)
Article DOI: 10.1016/j.bmcl.2017.03.082 BindingDB Entry DOI: 10.7270/Q2571F44 |
More data for this Ligand-Target Pair | |
Arginase-1
(Bos taurus) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by spectroscopic analysis |
Citation and Details
Article DOI: 10.1039/d0md00011f BindingDB Entry DOI: 10.7270/Q261140V |
More data for this Ligand-Target Pair | |
Autoinducer 2-binding periplasmic protein LuxP
(Vibrio harveyi) | BDBM26188
(α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University
Curated by ChEMBL
| Assay Description Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrs |
Bioorg Med Chem Lett 18: 1567-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.081 BindingDB Entry DOI: 10.7270/Q2DB81KV |
More data for this Ligand-Target Pair | |